Is their a way to create a custom Queue instead of the standard My Tickets, Group Tickets, Flagged Tickets listed at the top. To filter tickets that have been created with a certain label to filter into that clickable tab at the top?
No, but you can create a query (Tickets -> Search -> Advanced Search) and save it. then, anytime you are on a 'normal' ticket view like My Tickets or Group Tickets there is a dropdown at the top from which you can run your query as desired.