Here are some Knowledge Base entries that pertain to Orion NPM 9.5:
How do I enable CLR Integration for SQL Server 2005?
During an upgrade, I get an error at the end of the Configuration Wizard.
How do I fix a device that supports Cisco EnergyWise but doesn't appear to?
What does my DBA need to know about CLR Integration?
The Orion NPM 9.5 installation reports that there is a module incompatibility issue.