I can't change nothing in " Orion polling setting". I click on submit and nothing happens.
Someone have an idea ?
Step 1:
stop/restart all services, check deployment health, check that the DB is still connected, check the primary polling engine's logs.
Step 2:
Open a ticket and get them to look at things if not resolved from above.
I would also recommend trying a different browser
I made all of that unsuccessfully. I opened a ticket but I really think that my problem is due to Net Framework 4.8.
I have 4 servers and net Framework didn't install well on all of them.
That very well could be the issue. Weird things can and do often occur when there are differences in .NET Framework versions between Orion servers.
Tons of people (including MVP's) are having problems with the latest .net. I believe in some instances it gets uninstalled. On the same note, you need to make sure .net matches on all your servers as aLTeReGo notes or you get some really really unfun stuff such as just a menu bar, website doesn't load, etc.