Just upgraded to v10, no issues during the upgrade.
ipMonitor service runs as local account.
Using specific credentials for the SQL and Exchange monitors (same ones we used previously)
Now they are giving this: The remote device rejected the request due to an internal error and Unable to connect to the remote device.
Interestingly, when I do a 'verify' on a SQL monitor, it shows me results.. but the monitor itself still isn't working.