Unexpected error occured.
Insufficient memory to continue the exection of the program
I cant tell from the image, but are you just getting this message on specific monitors or against certain nodes?
The message you are receiving is the returned error from the node you are monitoring, so it is likely there are issues with that server. Check the memory and WMI status of that server.
It is useful in this instance to use something like WMI Explorer to isolate outside of Orion APM that the returned message is the same being presented to Orion.