I'm trying to get our Profiler instance to gather data from our vCenter server and am wondering what settings/plugins need to be enabled on the vCenter side in order for Profiler to communicate with the server at the https://servername/sdk/ address.
Nothing special is needed. Do you already have an STM Agent running on the IP Address you want to gather data from?
http://www.solarwinds.com/documentation/storage/storagemanager/OrionSTMAdministratorGuide.1.49.htm