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Is anyone using an F5 for load balancing the web front end?

I'm using an f5 LTM to load balance the web interface of my main polling server and additional web server (I'm also using it to load balance syslog and snap traps going to my three polling engines).  I have seen a loss of "save as PDF" functionality when I use the load balanced URL, but going directly to either web server, it works.  Has anyone else seen this?