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Below I am pasting two links for technical articles, which are explaining your issue.
Please note that when you use Windows Update and the new fixes includes dotNET or other library used by installed software, often this software is susceptible to issues.
Reboot will fix it, because all the libraries are reloaded. If SolarWinds agent depends on some of the fixes, in rare cases it may stop working correctly. This behaviour can be seen with all software, not only SolarWinds.
For example, deployment tools such as Altiris has mandatory reboot after upgrading and you often have 5-60 minutes to save current work and reboot, or Altiris will do it by itself.
I hope this will help you.
IT-Indago Ltd. - Authorized Reseller & SolarWinds Certified SCP Professional